Andy Robertson and Joe Gomez return to the Reds starting line-up at San Siro, replacing Conor Bradley and Milos Kerkez.
Elsewhere, Alexander Isak and Alexis Mac Allister come back into the XI, with Cody Gakpo absent due to injury and Florian Wirtz named among the substitutes.
Liverpool: Alisson, Gomez, Van Dijk, Konate, Szoboszlai, Isak, Mac Allister, Jones, Ekitike, Robertson, Gravenberch.
Subs: Mamardashvili, Woodman, Kerkez, Wirtz, Bradley, Nyoni, Ngumoha, Lucky.
